Weโve hit the business end of the college football season. Week 11 is where playoff dreams are solidified or shattered. The pretenders have been exposed. The contenders are making their final push for conference titles. The College football week 11 odds are set, the markets are hot, and the action is waiting right here.
College Football Week 11 Odds: The Marquee Matchups
This is where the season gets real. We have two massive ranked-on-ranked showdowns that will shake up the CFP landscape and define the conference races.
- No. 3 Texas A&M (-6) at No. 19 Missouri: The Aggies are in the driver’s seat for the SEC, but Memorial Stadium is a hostile environment. The Tigers are fighting for their playoff lives in a key SEC clash.
 
- No. 8 BYU at No. 9 Texas Tech (-10): This is the biggest matchup of the week, and ESPN’s “College GameDay” will be in Lubbock for it. The college football betting lines are locked as these two Top 10 teams square off in a game with massive implications.
 
CFP Contenders on Upset Alert
The top teams are facing tricky opponents, with many heading on the road. Don’t just look at the main Week 11 college football spreads; the real value might be in the college football alternate lines or live betting markets.
- No. 1 Ohio State (-29) at Purdue: The Buckeyes take their top-ranked show to West Lafayette.
 
- No. 2 Indiana (-14) at Penn State: The Hoosiers face a talented Penn State team desperate to snap a five-game losing streak. This game could be tougher than the line looks.
 
- No. 4 Alabama (-11) vs. LSU: It’s always a war when these two meet. Alabama looks to keep its playoff hopes pristine against a bitter rival at home.
 
- No. 5 Georgia (-7.5) at Mississippi State: The Bulldogs head to Starkville for a crucial SEC road test against the cowbells.
 
- No. 6 Oregon (-6) at Iowa: Coming off a bye, the Ducks travel to Iowa City. They need to keep winning to stay alive in the Big Ten title race.
 
Kicking Off the Week 11 College Football Betting
Get your weekend started early with two ranked teams under the Friday night lights.
- No. 20 Southern Cal (-14.5) vs. Northwestern (9 p.m., FOX)
 
- No. 22 Memphis (-6.5) vs. Tulane (9 p.m., ESPN)
 
The Best of the Rest: Week 11 Lines
From heavy favorites to potential trap games, here are the other key college football week 11 odds to track.
- No. 7 Ole Miss vs. The Citadel (1 p.m., SECN+)
 
- No. 10 Notre Dame (-26) vs. Navy (7:30 p.m., NBC)
 
- No. 12 Virginia (-7) vs. Wake Forest (7 p.m., ESPN)
 
- No. 14 Louisville (-19) vs. Cal (7 p.m., ESPN2)
 
- No. 15 Vanderbilt (-7) vs. Auburn (4 p.m., SEC Network)
 
- No. 18 Miami (Fla.) (-29) vs. Syracuse (3:30 p.m., ESPN)
 
- No. 24 Washington (-11) at Wisconsin (4:30 p.m., Big Ten Network)
 
Your Bet, Your Way
These are the featured games, but your college football Week 11 betting isn’t limited. Every game has a full board. Hunt for value on the college football moneylines, find an edge in the totals, or build a college football parlay that could deliver a massive payout. Grab the best college football betting lines before they move.
Lock In Your Action
The board is set. The stakes couldn’t be higher. Now it’s time to make your move. Review all the College football week 11 odds and lock in your bets. Whether you’re playing a single spread or crafting a multi-leg parlay, BetUS is your home for all the Week 11 action.